The Suprachoroid: Structure, Function, and Role in Eye Diseases

The suprachoroid is a layer of tissue that lies above the choroid, which is a layer of blood vessels that supplies the retina with oxygen and nutrients. The suprachoroid is a thin membrane that covers the sclera (the white part of the eye) and extends into the orbit (the bony cavity that contains the eyeball). It is composed of collagen fibers and is rich in blood vessels and nerve endings.

The suprachoroid plays an important role in maintaining the health and function of the retina, as it provides a supportive matrix for the choroidal blood vessels and helps to regulate the flow of fluid and nutrients between the choroid and the retina. It also serves as a barrier to protect the retina from external influences, such as injury or infection.

In addition to its structural and functional roles, the suprachoroid has been implicated in the development and progression of certain eye diseases, such as age-related macular degeneration (AMD) and diabetic retinopathy. For example, studies have shown that changes in the suprachoroidal tissue can lead to the formation of new blood vessels under the retina, which can contribute to the development of AMD.

Overall, the suprachoroid is a critical component of the eye's vascular system, and its structure and function are important for maintaining the health and function of the retina.