Understanding Ferrihemoglobin: Structure, Function, and Medical Applications

Ferrihemoglobin (HbFe) is a type of hemoglobin that contains iron (Fe) instead of the usual heme group. It is found in some species, including certain types of worms and insects, as well as in some mammals, such as the African elephant.

Ferrihemoglobin has a different structure and function compared to traditional hemoglobin, which is found in red blood cells of most vertebrates. In traditional hemoglobin, the heme group is responsible for binding oxygen and transporting it throughout the body. In ferrihemoglobin, the iron ion (Fe) is bound to the protein instead of the heme group, which allows it to bind oxygen as well.

Ferrihemoglobin has been studied for its potential use in medical applications, such as treating anemia and other blood disorders. It has also been used as a model system to study the structure and function of hemoglobin and other proteins.