Understanding Osteofibrous Dysplasia: Causes, Symptoms, and Treatment Options

Osteofibrous dysplasia (OFD) is a rare, non-malignant bone lesion that affects the long bones of the body, particularly the limbs. It is characterized by abnormal growth and development of bone tissue, leading to deformity and impaired function of the affected limb.

The term "osteofibrous" refers to the fact that this condition involves both bone and fibrous tissue. In OFD, there is an overgrowth of immature bone cells (osteoid) and a proliferation of fibrous tissue, which can lead to a variety of symptoms and complications.

The exact cause of osteofibrous dysplasia is not well understood, but it is thought to be related to genetic mutations or environmental factors that disrupt normal bone development. Treatment options for OFD vary depending on the severity of the condition and may include surgery, physical therapy, and medication.