Understanding Peliosis: Causes, Symptoms, and Treatment Options

Peliosis is a rare condition where the skin on the palms of the hands and soles of the feet becomes thick and hard. It is also known as "peliotic skin" or "pelioid skin."

The exact cause of peliosis is not fully understood, but it is thought to be related to changes in the skin's collagen structure and the accumulation of keratin, a protein found in skin and hair. The condition can occur at any age, but it is most common in adults between the ages of 20 and 50.

Peliosis typically affects both hands and feet equally, although one side may be more severely affected than the other. The skin on the palms and soles becomes thick and leathery, with a rough, sandpapery texture. The skin may also become discolored, with areas of darker or lighter pigmentation.

While peliosis is not harmful and does not cause any pain or discomfort, it can be unsightly and may affect an individual's self-esteem. Treatment for the condition typically involves topical creams or ointments to soften and smooth the skin, as well as protective measures such as wearing gloves or socks to prevent scratches and irritation. In severe cases, surgery may be necessary to remove the thickened skin.